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Medicin til lindring af smerter findes med forskellige aktive lægemiddelstoffer. Nogle er bedst egnet til for eksempel hovedpine og menstruationssmerter, imens andre er bedst egnet til ledsmerter og muskelsmerter.I dag er det ofte aflange tabletter. Her på apoteket kalder vi dem derfor ikke for smertestillende piller, Gentlemen for smertestillend